Study of complex formation in the “β cyclodextrin - p aminobenzoic acid” system
Анотація
Protolytic transitions of p‑aminobenzoic acid from molecular to anionic (or protonated) form were studied by UV spectroscopy. The change of ionization constants values as a result of p‑aminobenzoic acid localization in the hydrophobic cavity of β‑cyclodextrin was demonstrated. It was found that p‑amonobenzoic acid forms supramolecular structures with stoichiometric composition 1 : 1. The stability constants of “β‑cyclodextrin - p‑aminobenzoic acid” inclusion complex at 289, 292, 313 K and thermodynamic parameters involved in the complex formation (∆G°, ∆H°, ∆S°) were calculated.
Посилання
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