Lyposome prepfration for directed transportation of drugs
Анотація
The review is presents the results of the synthesis of liposomes for the targeted drug delivery into the tumor cells. The usage of the definite combination of saturated phospholipids and cholesterol leads to their stability increasing. On using unsaturated phospholipids for liposome preparation one could undertake precautions to minimize oxidation. Depending on the molar ratio of phospholipids and cholesterol, the size of magnetic liposomes is different. The liposomes of lesser diameter are preferable to larger ones because of their ability to escape phagocytosis by the cells of reticuloendothelial system and permeate from the bloodstream into the interstice easily. Among the liposomes, containing polyethylene glycol and antibodies, the most optimal ones are those, which contain the antibodies attached to distal edges of polyethylene glycol molecule chains. The antibody may be attached to polyethylene glycol molecule with the help of thioester or amide bond. In order to obtain sterically stabilized liposomes, water soluble carbodiimide should be taken.
Посилання
Uhumwangho M.U., Okor R.S. Current trends in the production and biomedical applications of liposomes: a review // JMBR: A Peer-review Journal of Biomedical Sciences. – 2005. – V. 4, № 1. – Р. 9 – 21.
Chelvi T.P., Ralhan R. Designing of thermosensitive liposomes from natural lipids for multimodality cancer therapy // International journal of hyperthermia. – 1995. – V. 11, № 5. – P. 685 – 695.
Preparation and characterization of manganese ferrite-based magnetic liposomes for hyperthermia treatment of cancer / А.P. Pradhan, J. Giri, R. Banerjee, J. Bellare, D. Bahadur // J. of Magnetism and Magnetic Materials. – 2007. – V. 311. – P. 208 – 215.
Paramagnetic thermosensitive liposomes for MR-thermometry / L.H. Lindner, M. Schlemmer, R. Stahl, M. Peller // International Journal of Hyperthermia. – 2005. – V. 21, № 6. – Р. 575 –588.
Thermosensitive liposomes and localised hyperthermia – an effective bimodality approach for tumour management / B. Tiwari Sandip, N. Udupa, B.S.S. Rao, P. Uma Devi // Indian Journal of Pharmacology. – 2000. – V. 32. – Р. 214 – 220.
Gaber M.H. Physicochemical properties of thermosensitive liposomes encapsulating fluorescein diphosphate // Romanian J. Biophys. – 2004. – V. 14, № 1 – 4. – P. 43 – 52.
Bangham A.D., Standish M.M., Watkins J.C. Diffusion of univalent ions across the lamellae of swollen phospholipids // J Mol Biol. – 1965. – V. 13. – P. 238 – 252.
Preparation of liposoms of defined size distribution by extrusion through polycarbonate membranes / F. Olson, C.A. Hunt, F.C. Szoka, W.J. Vail, D. Papahadjopoulos // Biochim Biophys Acta. – 1976. – V. 557. – P. 9 – 23.
Single bilayer liposomes // S.M. Johnson, A.D. Bangham, M.W. Hill, E.D. Korn // Biochim Biophys Acta. – 1971. – V. 233. – P. 820 – 826.
Nayar R., Hope M.J., Cullis P.R. Generation of large unilamellar vesicles from long-chain saturated phosphatidylcholine by extrusion techniques // Biochim Biophys Acta. – 1989. – V. 986. – P. 200 – 206.
Production of large unilamellar vesicles by a rapid extrusion procedure. Characterisation of size distribution, trapped volume and ability to maintain a membrane potential / M.J. Hope, M.B. Bally, G. Webb, P.R. Cullis // Biochim Biophys Acta. – 1985. –V. 812. – P. 55 – 65.
Amselem S., Gabizon A., Barenholz Y. A large-scale method for the preparation of sterile and non pyrogenic liposomal formulations of defined size distributions for clinical use. In: Gregoriadis G (Ed.). Liposome Technology. 2nd Edition. Boca Raton: CRC Press, 1993. – P. 501 – 525.
Generation of contrast-carrying liposomes of defined size with a new continuous high pressure extrusion method / T. Schneider, A. Sacfse, G. Robling, M. Brandl // Int J Pharm 1995. – V. 119. – P. 1 – 12.
Brunner J., Skrabai P., Hauser H. Single bilayer vesicles prepared without sonication. Physicochemical properties // BiochimBiophys Acta. – 1976. – V. 455. – P. 322 – 331.
Weiner N., Martin F., Riox M. Liposomes as drug delivery system // Drug Dev Ind Pharm. – 1989. – V. 15, № 10. – Р. 1523 – 1554.
Frezard F. Liposomes: from biophysics to the design of peptide vaccines // Braz J Biol Res. – 1999. – V. 32, № 2. – Р. 181 – 189.
Szoka F., Papahadjopoulos D. Procedure for preparation of liposomes with large internal aqueous space and high capture by reverse phase // Proceeding to the National Academy of Sciences. – 1978. – V. 75. – P. 4194 – 4198.
Liposomes containing modified cholesterol for organ targeting. United States Patent 4544545 (1985).
A new strategy for attachment of antibodies to sterically stabilized liposomes resulting in efficient targeting to cancer cells / T.M. Allen, E. Brandeis, C.B. Hansen, G.Y. Kao, S. Zalipsky // Biochimica et Biophysica Acta. – 1995. – V. 1237, № 2. – P. 99 – 108.
Цибулькина Е.А. Иммунолипосомальные системы направленного транспорта малых интерферирующих РНК в клетки-мишени // Автореферат дис. канд. хим. наук. – М., 2008.
Lasic D.D., Papahadjopoulos D. Liposomes revisited // Science. – 1995. – V. 267. – P. 1275 –1276.
Shi N., Pardridge W.M. Noninvasive gene targeting to the brain // PNAS. – 2000. – V. 97, № 13. – Р. 7567 – 7572.
Studies on protein−liposome coupling using novel thiol-reactive coupling lipids: influence of spacer length and polarity / M. Fleiner, P. Benzinger, T. Fichert, U. Massing // Bioconjugate Chem. – 2001. – V. 12, № 4. Р. 470 – 475.
Comparative studies of the preparation of immunoliposomes with the use of two bifunctional coupling agents and investigation of in vitro immunoliposome-target cell binding by cytofluorometry and electron microscopy / R.A. Schwendener, T. Trüb, H. Schott, H. Langhals, R.F. Barth, P. Groscurth, H. Hengartner // Biochimica et Biophysica Acta. – 1990. – V. 1026, № 1. – Р. 69 – 79.
Sullivan S.M., Huang L. Preparation and characterization of heat-sensitive immunoliposomes // Biochimica et Biophysica Acta. – 1985. – V. 812, № 1. – Р. 116 – 126.
(WO/1999/066964) Сarbodiimide cross-linked albumin for bioadhesives, surgical sealants and implantable devices.
US Patent 4814098 - Magnetic material-physiologically active substance conjugate.
(WO/2003/031975) Homogeneous ligand binding assay.
Antibody-conjugated magnetoliposomes for targeting cancer cells and their application in hyperthermia / M. Shinkai, M. Suzuki, S. Iijima, T. Kobayashi // Biotechnology and applied biochemistry. – 1995. – V. 21, № 2. – Р. 125– 137.
Immunopotentiators in thermotherapy for cancer / T. Kobayashi, M. Shinkai, H. Honda, K. Ueno, K. Ohtsuka // European Patent EP1438971, 07/21/2004.
Preparation and characterization of manganese ferrite-based magnetic liposomes for hyperthermia treatment of cancer / P. Pradhan, J. Giri, R. Banerjee, J. Bellare, D. Bahadur // Journal of magnetism and magnetic materials. – 2007. – V. 311. – P. 208 – 215.
Microencapsulation of hemoglobin in liposomes using a double emulsion, film dehydration/rehydration approach / S. Zheng, Y. Zheng, R.L. Beissinger, R. Fresco // Biochim. Biophys. Acta. – 1994. – V. 1196. – P. 123 – 130.
Nawroth T., Rusp M., May R.P. Magnetic liposomes and entrapping : time-resolved neutron scattering TR-SANS and electron microscopy // Physica B. – 2004. – V. 350. – P. 635 – 638.
Synthesis and characterization of ultrafine well-dispersed magnetic nanoparticles / Z.L. Liu, H.B. Wang, Q.H. Lu, G.H. Du, L. Peng, Y.Q. Du, S.M. Zhang, K.L. Yao // J. Magn. Magn. Mater. – 2004. – V. 283. – P. 258 – 262.
Attachment of water-soluble proteins to the surface of (magnetizable) phospholipid colloids via neutravidin-derivatized phospholipids / M. De Cuyper, M. Hodenius, Z.G.M. Lacava, R.B. Azevedo, M. de F´atima da Silva, P. Cesar Morais, M. Helena Andrade Santana // J. Colloid and Interface Sci. – 2002. – V. 245. – P. 274 – 280.
