Adsorption of bioactive molecules of medicinal plants

  • V. K. Pogorelyi Інститут хімії поверхні НАН України
  • V. N. Barvinchenko Інститут хімії поверхні НАН України
  • N. A. Lipkovska Інститут хімії поверхні НАН України
  • V. V. Turov Інститут хімії поверхні НАН України
  • A. A. Chuiko Інститут хімії поверхні НАН України

Анотація

The adsorption of some herbal bioactive polyphenolics (anthraquinones, flavons) from solutions of different polarity onto a surface of highly dispersed silica (entherosorbent Silics) is studied. It is found that the structure of adsorption complexes and the mechanism of their formation depend essentially on the solvent nature. Preliminary clinical researches have shown high medecinal activity of Phytosil composites regarding children’s herpes stomatitis. The effectiveness of Phytosil composite corresponds to the level of thymic immunostimulators, but its application makes the process of treatment simpler and cheaper.

Посилання

Chuiko A.A., Pentyuk O.O , Scientific Principles of Development of Medicinal Preparations on the basis of Highly Disperse Silica// Proc. of the Scientific Session of the Department of Chemistry of the NAS of Ukraine Dedicated to the 80th Anniversary of the NAS of Ukraine, Kharkiv, June 9-11, 1998, Book Abstr. pp. 36-51. (in Russian).

Georgievskii V.P., Komisarenko N.F., Dmitruk S.E., Biologically Active Substances of Medicinal Plants. Novosibirsk: Nauka, 1990,- 332 p.

Chuiko A.A., Gorlov Yu.I. Surface Chemistry of Silica: Surface Structure, Active Sites, Sorption Mechanisms, Kyiv: Naukova Dumka, 1992. - 248 p. (in Russian).

Kovtyukhova N.I., Pogorelyi V.K. The adsorption of bioactive polyphenols on silica oxide from inert solvents // Ukr. Khim. Zh.- 1997. - V.63, N 1-2,- P.20-25. (in Russian).

Iler R.K., The Chemistry of Silica: Solubility, Polymerization, Colloid and Surface Properties, and Biochemistry. New York - Chichester - Brisbane - Toronto: A Wiley- Interscience Publication, 1979. - 1127 p.

Tentsova A.I. (Ed.), Pharmacist Reference Book, Meditsina, Moscow, 1981. - 354 p. (in Russian).

Georgievskii V.P., Konev F.A.(Eds), Technology and Standardization of Medicinal Substances. Khar’kov: “RIREG”, 1996. - 784 p. (in Russian).

Turov V.V., Barvinchenko V.N. Structurally ordered surface layers of water at the Si02/ice interface and influence of adsorbed molecules of protein hydrolysate on them// Colloids and Surf. B. - 1997. - N. 8. -P. 125-132.

Study of interaction of albumine serum with dymethylsulfoxide on PMR spectra of the frozen water solutions / V.K. Pogorelyi, V.V. Turov, A.V. Turov, V.N.Barvinchenko // Teor.Eksp.Khim,- 1989,- V. 25,N 1,- P.104-108. (in Russian).

Turov V.V., Leboda R. Application of H1 NMR spectroscopy method for determination of haracteristics of thin layer of water adsorbed on the surface of dispersed and porous adsorbents // Colloid and Interface Sci.- 1999. - V. 79. - P.173-211.

The investigation of physico-chemical and clinical properties of medicine composites belonging to the Phytosil family/ A.A. Chuiko, V.K. Pogorelyi, V.N. Barvinchenko, N.A.Lipkovska, N.I.Kovtyukhova, V.V. Turov // Visnyk Vinnyts’kogo Derzhavnogo Medychnogo Universytetu.- 1999. - N 3,- P. 253-256. (in Ukrainian).

Опубліковано
2001-06-10
Як цитувати
Pogorelyi, V. K., Barvinchenko, V. N., Lipkovska, N. A., Turov, V. V., & Chuiko, A. A. (2001). Adsorption of bioactive molecules of medicinal plants. Поверхня, (4-6), 301-309. вилучено із http://surfacezbir.com.ua/index.php/surface/article/view/69