Медичні нанокомпозити на базі гідрофільних та гідрофобних кремнеземів та їхні властивості
Анотація
Розроблено технології для виробництва нанокомпозитних систем на основі гідрофільних та гідрофобних кремнеземів або їх сумішей з біологічно активними сполуками рослинного походження, такими як бетулін, пектин та інулін. Були досліджені фізико-хімічні властивості та структура адсорбційного шару, а також визначені співвідношення концентрацій компонентів, за яких активні речовини знаходяться в своєму найбільш активному, нанорозмірному стані. Отримано інформацію про можливості регулювання швидкості вивільнення біологічно активних компонентів з композитних систем. Інулін та інші біоактивні речовини (БАР) утворюють композитні системи з гідрофільним або сумішшю гідрофільного та гідрофобного кремнезему під час механічної обробки, зберігаючи високу питому поверхню композитної системи. Водночас БАР рівномірно розподілені на поверхні мінеральних частинок. Як у вихідних матеріалах, так і в композитних системах адсорбована вода знаходиться у вигляді нано- або субнанорозмірних кластерів, утворених сильноасоційованою водою, молекули якої одночасно беруть участь в утворенні 2–3 водневих зв'язків. Слабкополярне органічне середовище має розупорядкувальний (хаотропний) вплив на воду. Зі зниженням температури впорядкування адсорбованих молекул води збільшується, хоча в деяких системах фіксовані температурні інтервали, за яких відбувається космотропний вплив поверхні на адсорбовану воду. Додавання гідрофобного кремнезему AM1 до композитної системи A-300/БАР приводить до збільшення взаємодії між поверхнею та водою. Величина міжфазної енергії корелює зі зменшенням радіуса адсорбованих кластерів води. Водні гелі, створені з діоксиду кремнію та БАР, демонструють властивості неньютонівських рідин, які, залежно від величини деформації зсуву, можуть проявляти як псевдопластичні, так і дилатаційні властивості.
Посилання
Ashton S., Song Y. H., Nolan J., Cadogan E., Murray J., Odedra R., Foster J., Hall P. A., Low S., Taylor P., Ellston R., Polanska U. M., Wilson J., Howes C., Smith A., Goodwin R. J. A., Swales J. G., Strittmatter N., Takáts Z., Nilsson A., Andren P., Trueman D., Walker M., Reimer C. L., Troiano G., Parsons D., Witt D. De., Ashford M., Hrkach J., Zale S., Jewsbury Ph. J., Barr S. T. Aurora kinase inhibitor nanoparticles targets tumors with favorable therapeutic index in vivo. Sci. Transl. Med. 2016. 8(325): 325ra17. https://doi.org/10.1126/scitranslmed.aad2355
Bawa R., Audette G. F., Reese B. E. Handbook of clinical nanomedicine: law, business, regulation, safety, and risk. (Pan Stanford Publishing, 2016). https://doi.org/10.1201/b19910
Nair M., Guduru R., Liang P., Hong J., Sagar V., Khizroev S. Externally controlled on-demand release of anti-HIV drug using magneto-electric nanoparticles as carriers. Nat. Commun. 2013. 4(1): e1707. https://doi.org/10.1038/ncomms2717
Ward E. M., Sherman R. L., Henley S. J., Jemal A., Siegel D. A. Feuer E. J., Firth A. U, Kohler B. A., Scott S., Ma J., Anderson R.N., Benard V., Cronin K.A. Annual report to the nation on the status of cancer, featuring cancer in men and women age 20-49 years. J. Natl. Cancer Inst. 2019. 111(12): 1279. https://doi.org/10.1093/jnci/djz106
Yang J., Wang Z., Zong S., Chen H., Zhang R., Cui Y. Dual-mode tracking of tumor-cell-specific drug delivery using fluorescence and label-free SERS technique. Biosens. Bioelectron. 2014. 51: 82. https://doi.org/10.1016/j.bios.2013.07.034
Gray M. D., Lyon P. C., Mannaris C., Folkes L. K., Stratford M., Campo L. Focused ultrasound hyperthermia for targeted drug release from thermosensitive liposomes: results phase I trial. Radiol. 2019. 291: 232. https://doi.org/10.1148/radiol.2018181445
Turov V. V., Krupska T. V., Guzenko N. V., Borysenko M. V., Nychiporuk Yu. M., Gun'ko V. M. Controlled confined space effects on clustered water bound to hydrophobic nanosilica with nonpolar and polar co-adsorbates. Colloid. and Surf. A: Physicochem. and Engin. Aspects. 2022. 644: e 128919. https://doi.org/10.1016/j.colsurfa.2022.128919
Turov V. V., Gerashchenko I. I., Krupskaya T. V., Suvorova L. Nanochemistry in solving problems of exo- and endoecology. (Stavropol: Zebra, 2017.) [in Russian]
Gun'ko V. M., Turov V. V., Pakhlov E. M., Krupska T. V., Borysenko M. V., Kartel M. T., Charmas Barbara Water Interactions with Hydrophobic versus Hydrophilic Nanosilica Langmuir. 2018. 34: 12145. https://doi.org/10.1021/acs.langmuir.8b03110
Gun'ko V. M., Turov V. V., Pakhlov E. M., MatkovskyA. K., Krupska T. V., Kartel M. T., Charmas Barbara Blends of amorphous/crystalline nanoalumina and hydrophobic amorphous nanosilica. J. Of Non-Crystalline Solids. 2018. 500: 351. https://doi.org/10.1016/j.jnoncrysol.2018.08.020
Muller V. M. Theory of reversible coagulation. Colloid Journal. 1996. 58(5): 634. [in Russian]
Efremov I.F. Periodic colloidal structures. (Leningrad: Chemistry, 1971). [in Russian]
Turov V. V., Krupska T. V. Influence of mechanical loads on the state of water in the hydrophobic environment of methyl silica particles. Theor. Exp. Chem. 2022. 58(1); 48. https://doi.org/10.1007/s11237-022-09721-w
Turov V. V., Gun'ko V. M., Turova A. A. Morozova L. P., Voronin E. F. Interfacial behavior of concentrated HCl solution and water clustered at a surface of nanosilica in weakly polar solvents media. Coll. Surf. A: Physicochem. Engin. Aspects. 2011. 390(1-3): 48 https://doi.org/10.1016/j.colsurfa.2011.08.053
Gun'ko V. M., Turov V. V., Turov A. V. Hydrogen peroxide - water mixture bound to nanostructured silica. Chem. Phys. Lett. 2012. 531: 132. https://doi.org/10.1016/j.cplett.2012.01.090
Gun'koV. M., Turov V. V., Pakhlov E. M., KrupskaT. V., Charmas B. Effect of water content on the characteristics of hydro-compacted nanosilica. Applied Surf. Scien. 2018. 459: 171. https://doi.org/10.1016/j.apsusc.2018.07.213
Gun'ko V. M. Morphological and textural features of various materials composed of porous or nonporous nanoparticles differently packed in secondary structures. Applied Surf. Science. 2021. 569: 151117. https://doi.org/10.1016/j.apsusc.2021.151117
Gregg S. J., Sing K. S. W. Adsorption, Surface Area and Porosity. (London: Academic Press,1982).
Adamson A. W., Gast A. P. Physical Chemistry of Surface. Sixth edition. (New York: Wiley, 1997).
Rüger R., Franchini M., Trnka T., Yakovlev A., van Lenthe E., Philipsen P., van Vuren T., Klumpers B., Soini N. AMS 2024.102. SCM, Theoretical Chemistry, Vrije Universiteit, Amsterdam, The Netherlands. Available online: https://www.scm.com (accessed on 6 February 2024).
Stewart J. J. P. MOPAC 2022.1.1, Stewart Computational Chemistry. Available online: http://OpenMOPAC.net (accessed on 6 February 2024).
Gun'ko V. M., Turov V. V. Nuclear Magnetic Resonance Studies of Interfacial Phenomena. (CRC Press, Boca Raton. 2013). https://doi.org/10.1201/b14202
Strange J. H., Rahman M., Smith E. G. Characterization of porous solids by NMR. Phys. Rev. Lett. 1993. 71: 3589. https://doi.org/10.1103/PhysRevLett.71.3589
Mitchell J., Webber J. B. W., Strange J. H. Nuclear magnetic resonance cryoporometry. Phys. Rep. 2008. 461: 1. https://doi.org/10.1016/j.physrep.2008.02.001
Kimmich R. NMR Tomography, Diffusometry, Relaxometry. (Springer: Heidelberg, 1997).
Ow Y. Y., Stupans I. Gallic acid and gallic acid derivatives: effects on drug metabolizing enzymes. Curr. Drug Metab. journal. 2003. 4(3): 241 PMID 12769668. https://doi.org/10.2174/1389200033489479
Gu C., Howell K., Dunshea F. R., Suleria H. A. R. LC-ESI-QTOF/MS characterisation of phenolic acids and flavonoids in polyphenol-rich fruits and vegetables and their potential antioxidant activities. Antioxidants Basel. 2019. 8(9): 405, https://doi.org/10.3390/antiox8090405
Balkrishna A., Pokhrel S., Tomer M., Verma S., Kumar A., Nain P., Gupta A., Varshney A. Anti-acetylcholin esterase activities of mono-herbal extracts andexhibited synergistic effects of the phytoconstituents: a biochemical and computational study. Molecules. 2019. 24(22):4175. https://doi.org/10.3390/molecules24224175
Govea-Salas M., Rivas-Estilla A. M., Rodríguez-Herrera R., Lozano-Sepúlveda S. A., Aguilar-Gonzalez C. N., Zugasti-Cruz A., Salas-Villalobos T. B., Morlett-Ch'avez J. A. Gallic acid decreases hepatitis C virus expression through its antioxidant capacity. Exp. Ther. Med. 2016. 11(2): 619. https://doi.org/10.3892/etm.2015.2923
Nouri A., Heibati F., Heidarian E. Gallic acid exerts anti-inflammatory, anti-oxidative stress, and nephroprotective effects against paraquat-induced renal injury in male rats. Naunyn Schmiedebergs Arch. Pharmacol. 2020. 394: 1. https://doi.org/10.1007/s00210-020-01931-0
BenSaad L. A., Kim K. H., Quah C. C., Kim W. R., Shahimi M. Anti-inflammatory potential of ellagic acid, gallic acid and punicalagin A&B isolated from Punica granatum. BMC Complement, Altern. Med. 2017. 17(1): 47. https://doi.org/10.1186/s12906-017-1555-0
Bai Jinrong, Zhang Yunsen, Tang Ce, Houa Ya, Ai Xiaopeng, Chen Xiaorui, Zhang Yi, Wang Xiaobo, Meng Xianli Gallic acid: Pharmacological activities and molecular mechanisms involved in inflammation-related diseases. Biomedicine & Pharmacotherapy. 2021. 133: e110985. https://doi.org/10.1016/j.biopha.2020.110985
Hashimoto O., Kuniishi H., Nakatake Y., Yamada M., Wada K., Sekiguchi M. Dexamethasone-loaded HO-activatable anti-inflammatory nanoparticles for on-demand therapy of inflammatory respiratory diseases. Nanomedicine. 2020. 14: e102301. https://doi.org/10.1016/j.nano.2020.102301
Lima K. G., Krause G. C., Schuster A. D., Catarina A. V., Basso B. S., De Mesquita F. C., Pedrazza L., Marczak E. S., Martha B. A., Nunes F. B., Chiela E. C. F., Jaeger N., Thom'e M. P., Haute G. V., Dias H. B., Donadio M. V., De Oliveira J. R. Gallic acid reduces cell growth by induction of apoptosis and reduction of IL-8 in HepG2 cells. Biomed. Pharmacother. 2016. 84: 1282. https://doi.org/10.1016/j.biopha.2016.10.048
Ho H. H., Chang C. S., Ho W. C., Liao S. Y., Lin W. L., Wang C. J. Gallic acid inhibits gastric cancer cells metastasis and invasive growth via increased expression of RhoB, downregulation of AKT/small GTPase signals and inhibition of NF-κB activity. Toxicol. Appl. Pharmacol. 2013. 266(1): 76. https://doi.org/10.1016/j.taap.2012.10.019
Schimites P. I., Segat H. J., Teixeira L. G., Martins L. R., Mangini L. T., Baccin P. S., Rosa H. Z., Milanesi L. H., Burger M. E., Soares A. V. Gallic acid prevents ketamine-induced oxidative damages in brain regions and liver of rats. Neurosci. Lett. 2020. 714: e134560. https://doi.org/10.1016/j.neulet.2019.134560
Vuolo M. M., Batista A. G., Biasoto A. C. T., Correa L. C., Júnior M. R. M., Liu R. H. Red-jambo peel extract shows antiproliferative activity against HepG2 human hepatoma cells. Food Res, Int. 2019. 124: 93. https://doi.org/10.1016/j.foodres.2018.08.040
Shahrzad S., Aoyagi K., Winter A., Koyama A., Bitsch I. Pharmacokinetics of gallic acid and its relative bioavailability from tea in healthy humans. J. Nutr. 2001. 131(4): 1207. https://doi.org/10.1093/jn/131.4.1207
Zhong Y. X., Jin X. L., Gu S. Y., Peng Y., Zhang K. R., Ou-Yang B. C., Wang Y., Xiao W., Wang Z. Z., Aa J. Y., Wang G. J., Sun J. G. Integrated identification, qualification and quantification strategy for pharmacokinetic profile study of Guizhi Fuling capsule in healthy volunteers. Sci. Rep. 2016. 6: e 31364. https://doi.org/10.1038/srep31364
Zhu H., Liu X., Zhu T. T., Wang X. L., Qin K. M., Pei K., Cai B. C. UHPLC-MS/MS method for the simultaneous quantitation of five anthraquinones and gallic acid in rat plasma after oral administration of prepared rhubarb decoction and its application to a pharmacokinetic study in normal and acute blood stasis rats. J. Sep. Sci. 2017. 40(11): e 2382. https://doi.org/10.1002/jssc.201700166
Tsang M. S., Jiao D., Chan B. C., Hon K. L., Leung P. C., Lau C. B., Wong E. C., Cheng L., Chan C. K., Lam C. W., Wong C. K. Anti-inflammatory activities of Pentaherbs Formula, Berberine, gallic acid and chlorogenic acid in atopic dermatitis-like skin inflammation. Molecules. 2016. 21(4): 519. https://doi.org/10.3390/molecules21040519
Yoon C. H., Chung S. J., Lee S. W., Park Y. B., Lee S. K., Park M. C. Gallic acid, a natural polyphenolic acid, induces apoptosis and inhibits proinflammatory gene expressions in rheumatoid arthritis fibroblast-like synoviocytes. Joint Bone Spine. 2013. 80(3): 274. https://doi.org/10.1016/j.jbspin.2012.08.010
Correa L. B., P'adua T. A., Seito L. N., Costa T. E., Silva M. A., Cand'ea A. L., Rosas E. C., Henriques M. G. Anti-inflammatory effect of Methyl Gallate on experimental arthritis: inhibition of neutrophil recruitment, production of inflammatory mediators, and activation of macrophages. J. Nat. Prod. 2016. 79(6): 1554. https://doi.org/10.1021/acs.jnatprod.5b01115
Kononova P. A., Selyutina O. Y., Polyakov N. E. Glycyrrhizic acid as a multifunctional drug carrier - From physicochemical properties to biomedical applications: A modern insight on the ancient drug. Membranes. 2023. 13(5): 505.
Selyutina Yu., Kononova P. A., Polyakov N. E. Effect of glycyrrhizic acid on phospholipid membranes in media with different pH. Russ Chem Bull. 2021. 70(12): 2434. https://doi.org/10.1007/s11172-021-3364-3
Selyutina O. Y., Polyakov N. E. Glycyrrhizin-Assisted Transport of Praziquantel Anthelmintic Drug through the Lipid Membrane: An Experiment and MD Simulation. Int. J. Pharm. 2019. 559: 271.
Kim A.V., Shelepova E.A., Selyutina O.Y., Meteleva E.S., Dushkin A.V., Medvedev N.N., Polyakov N.E., Lyakhov N.Z. Glycyrrhizic acid: A promising carrier material for anticancer therapy. Mol Pharm. 2019. 16(7): 3188 https://doi.org/10.1021/acs.molpharmaceut.9b00390
Abragam A. Principles of nuclear magnetic resonance. (Oxford: Oxford Science Publcations. 1989).
Gun'ko V. M., Turov V. V. Interfacial Phenomena in Nanostructured Systems with Various Materials. ChemPhysChem. 2024. 25(6): e202300622. https://doi.org/10.1002/cphc.202300622
Thermodynamic properties of individual substances. (edited by V.P. Glushko). (Moscow: Science, 1978). [in Russian].
Haddad Y. M. Viscoelasticity of Engineering Materials. (London: Chapman and Hall, 1995). https://doi.org/10.1007/978-94-011-1272-7
Gentile L., Silva B.F., Balog S., Mortensen K., Olsson U. Structural transitions induced by shear flow and temperature variation in a nonionic surfactant/water system. J. of Coll. and Interf. Sci. 2012. 372: 32. https://doi.org/10.1016/j.jcis.2012.01.027
Giomi L., Liverpool T. B., Marchetti M. C. Sheared active fluids: Thickening, thinning, and vanishing viscosity. Physical Review E. 2010. 81: e051908. https://doi.org/10.1103/PhysRevE.81.051908
Hatwalne Y., Ramaswamy S., Rao M., Simha R. A. Rheology of Active-Particle Suspensions. Phys. Rev. Lett. 2004. 92: e118101. https://doi.org/10.1103/PhysRevLett.92.118101
Kuo-Hsiung Lee, Morris-Natschke Susan Recent advances in the discovery and development of plant-derived natural products and their analogs as anti-HIV agents. Pure and Appl. Chem. 1999. 71(6): 1045. https://doi.org/10.1351/pac199971061045
Patent US 5962527. Pezzuto J. M., Dac Gupta T. P., Schmidt M. L., Kuzmanoff K. M., Ling-Indeck L., Kim Darrick S. H. L. Methods and composition for treating cancers. 1999.
Drag M., Surowiak P., Drag-Zalesinska M., Dietel M., Lage H., Oleksyszyn J. Comparison of the Cytotoxic Effects of Birch Bark Extract. Betulin and Betulinic Acid Towards Human Gastric Carcinoma and Pancreatic Carcinoma Drug-sensitive and Drug-Resistant Cell Lines. Molecules. 2009. 14(4): 1639. https://doi.org/10.3390/molecules14041639
Pokrovsky A. G., Plyasunova O. A., Ilyicheva T. N. Synthesis of derivatives of plant triterpenes and study of their antiviral and immunostimulating activity. Chemistry for sustainable development. 2001. 9: 485.
Lavoie Serge, Pichette Andre, Garneau Francois-Xavier, Girard Michel, Gaudet Daniel Synthesis of betulin derivatives with solid supported reagents (Laseve, Univ. du Quebec a Chicoutimi, 555 boul. Univ., Chicoutimi, Quebec, Canada, G7H 2B1). Synth. Commun. 2001. 31(10): 1565. https://doi.org/10.1081/SCC-100104070
Khlebnikova T. B., Pai Z. P., Kuznetsov B. N., Matzat Yu. V., Kuznetsova S. A., Berdnikova P. V., Skvortsova G. P. Catalytic oxidation of betulin and betulin diacetate using environmentally friendly oxidizing agents. J. of the Siber. Fed. Univ. Chem. 2008. (3): 277. [in Russian]
Kuznetsova S. A., Vasil'eva N. Yu., Kalacheva G. S., Titova N. M., Redkina E. S., Skvortsova G. P. Obtaining Betulin Diacetate from Outer Birch Bark and Studying its Antioxidant Activity. J. of the Siber. Fed. Univ. Chem. 2008. 2: 151.
Levdansky V.A. Condensation products of betulinic acid with some aliphatic amines and amino acids. J. of the Siber. Fed. Univ. Chem. 2008. 1: 88.
Kogay T.I. An improved two-stage method for obtaining betulinic acid from botulin. J. of the Siberian Federal University. Chemistry. 2008. 1: 97.
Kogay T.I., Kuznetsov B.N. Reduction of betulonic acid to betulinic acid under conditions of interfacial catalysis. Chemistry of plant raw materials. 2008. 2. 95.
Liby K.T., Yore M.M., Sporn M.B. Triterpenoids and rexinoids as multifunctional agents for the prevention and treatment of cancer. Nat. Rev. Cancer. 2007. 7(5): 357. https://doi.org/10.1038/nrc2129
Hsu T.-I., Chen Y.-J., Hung C.-Y., Wang Y.-C., Lin S.-J., Su W.-C., Lai M.-D., Kim S.-Y., QiangW., Keduo Q., Goto M., Zhao Y., Kashiwada Y., Lee K.-H., Chang W.-Ch., Hung J.-J. A novel derivative of betulinic acid, SYK023, suppresses lung cancer growth and malignancy. Oncotarget. 2015. 6(15): 13671. https://doi.org/10.18632/oncotarget.3701
Alakurtti S., Mäkelä T., Koskimies S., Yli-Kauhaluoma J. Pharmacological properties of the ubiquitous natural product betulin. Eur. J. Pharm. Sci. 2006. 29(1): 1. https://doi.org/10.1016/j.ejps.2006.04.006
Lin W. Y., Lin F. H., Sadhasivam S., Savitha S. Antioxidant effects of betulin on porcine chondrocyte behavior in gelatin/C6S/C4S/HA modified tricopolymer scaffold. Mater. Sci. Eng. C. 2010. 30(4): 597. https://doi.org/10.1016/j.msec.2010.02.010
Chintharlapalli S., Papineni S., Ramaiah S. K., Safe S. Betulinic acid inhibits prostate cancer growth through inhibition of specificity protein transcription factors. Cancer Res. 2007. 67(6): 2816. https://doi.org/10.1158/0008-5472.CAN-06-3735
Yogeeswari P., Sriram D. Betulinic Acid and Its Derivatives: A Review on their Biological Properties. Curr. Med. Chem. 2005. 12(6): 657. https://doi.org/10.2174/0929867053202214
Fulda S. Betulinic acid for cancer treatment and prevention. Int. J. Mol. Sci. 2008. 9(6) 1096. https://doi.org/10.3390/ijms9061096
Gao Yang, Ma Qing, Ma Yan-Bin, Ding Liang, Xu Xiao-Long, Wei De-Fei, Wei Lei, Zhang Jing-Wei Betulinic acid induces apoptosis and ultrastructural changesin MDA-MB-231breast cancer cells. Ultra Pathol. 2018. 42(1): 49. https://doi.org/10.1080/01913123.2017.1383548
Jäger S., Laszczyk M. N., Scheffler A. A preliminary pharmacokinetic study of betulin, the main pentacyclic triterpene from extract of outer bark of birch (Betulae albacortex). Molecules. 2008. 13(12): 3224 https://doi.org/10.3390/molecules13123224
Hordyjewska A., Ostapiuk A., Horecka A. Betulin and betulinic acid in cancer research. J. Pre Clin Clin Res. 2018. 12(2): 72 https://doi.org/10.26444/jpccr/92743
Wiggins P. M., MacClement B. A. E. Two States of Water Found in Hydrophobic Clefts: Their Possible Contribution to Mechanisms of Cation Pumps and Other Enzymes. Internat. Rev. Cytol. 1987. 108: 249. https://doi.org/10.1016/S0074-7696(08)61440-0
Dore J. Structural Studies of Water in Cinfined Geometry bu Neutron Difraction. Chem. Phys. 2000. 258: 327. https://doi.org/10.1016/S0301-0104(00)00208-1
Chaplin M. F. A Proposal for Structuring of Water. Biophys. Chem. 1999. 83: 211. https://doi.org/10.1016/S0301-4622(99)00142-8
Wiggins P. M. Role of Water in Some Biological Proceses. Microbiol. Rev. 1990. 54: 432. https://doi.org/10.1128/mr.54.4.432-449.1990
Wiggins P. M. High- and Low-Density Water in Gel. Progr. Polim. Sci. 1995. 20: 1121. https://doi.org/10.1016/0079-6700(95)00015-8
Wiggins P. M. High- and Low-Density Intracellular Water. Coll. Mol. Biol. 2001. 47: 735.
Galkin A. A., Lunin V. V. Water in sub- and supercritical states − a universal medium for the implementation of chemical reactions. Uspekhi Chemistry. 2005. 74(1): 24. https://doi.org/10.1070/RC2005v074n01ABEH001167
Marsall W., Jones E. Liquid-vapor critical temperatures of aqueous electrolyte solutions. J. Inorg. Nucl. Chem.1974. 36(10): 2313. https://doi.org/10.1016/0022-1902(74)80275-7
Turov V. V., Leboda R. Application of 1H NMR Spectroscopy Method for Determination of Characteristics of Thin Layers of Water Adsorbed on the Surface of Dispersed and Porous Adsorbents. Adv. Colloid Interface Sci. 1999. 79: 173. https://doi.org/10.1016/S0001-8686(97)00036-5
Gunko V. M., Turov V. V., Gorbik P. P. Water at the interface. (Kyiv: Naukova Dumka, 2009).
Gun'ko V. M., Turov V. V. Structure of Hydrogen Bonds and 1H NMR Spectra of Water at the Interface of Oxides. Langmuir. 1999. 15: 6405. https://doi.org/10.1021/la9809372
Gun'ko V. M., Turov V. V., Bogatyrev V. M., Zarko V. I., Leboda R., Goncharuk E. V., Novza A. A., Turov A. V., Chuiko A. A. Unusual Properties of Water at Hydrophilic/Hydrophobic Interfaces. Adv. Colloid Interf. Sci. 2005. 118: 125 . https://doi.org/10.1016/j.cis.2005.07.003
Turov V. V., Leboda R. 1H NMR Spectroscopy of adsorbed molecules and free surface energy of carbon adsorbents. Physical and Chemistry of Carbons. 2000. 27: 67.
Turov V. V., Gun'ko V. M. Bogatyrev V. M., Zarko V. I., Gorbik S. P., Pakhlov E. M., Leboda R., Shulga O. V., Chuiko A. A. Structured Water in Partially Dehydrated Yeast Cells and at Partially Hydrophobized Fumed Silica Surface. J. Colloid Interface Sci. 2005. 283: 329. https://doi.org/10.1016/j.jcis.2004.09.046
Tassaing T., Danten Y., Besnard M. Supercritical water: Local or molecular dynamics. Pure Appl. Chem. 2004. 76(1): 133. https://doi.org/10.1351/pac200476010133
Patent UA 138023. Krupska T. V., Turov V. V., Gunko V. M., Kartel M. T. The method of transferring in water the middle of the sum of hydrophilic and hydrophobic silicas in the path of victoria of high mechanical strength. 2019. [in Ukrainian]
Patent UA 138129. Krupska T. V., Turov V. V., Kartel M. T. The method of transferring hydrophobic silica in the middle waterway through the path of high mechanical strength. 2019.
Turov V. V., Gunko V. M. Clustered water and ways of its use. (Kyiv: Naukova Dumka. 2011. - 316 p.
Emsley J. W., Feenej J., Sutcliffe L. H. High Resolution Nuclear Magnetic Resonance Spectroscopy. (Oxford: Pergamon Press. 1965). https://doi.org/10.1016/B978-0-08-002792-0.50007-4
Bell A. T., Pines A. (Eds) NMR techniques in catalysis. (New York: Marcel Dekker. 1994).
Brunner E., Pfeifer H. NMR spectroscopic techniques for determining acidity and basicity. Molecular sieves. 2008. 6: 1. (In: Karge H. G., Weitkamp J. (Eds) Acidity and Basicity. Springer) https://doi.org/10.1007/3829_2007_016
Medical chemistry and clinical application of silicon dioxide. (Edited by O.O. Chuiko). (Kyiv: Naukova Dumka, 2003). [in Ukrainian]
Dening T. J., Rao S., Thomas N., Prestidge C. A. Novel nanostructured solid materials for modulating oral drug delivery from solid-state lipid-based drug delivery systems. AAPS J. 2016. 18(1): 23. https://doi.org/10.1208/s12248-015-9824-7
Turov V. V., Gun'ko V. M., Pakhlov E. M., Krupska T. V., Tsapko M. D., Charmas B., Kartel M. T. Influence of hydrophobic nanosilica and hydrophobic medium on water bound in hydrophilic components of complex systems. Colloids Surf. A. Physicochem. Eng. Asp. 2018. 552(5): 39. https://doi.org/10.1016/j.colsurfa.2018.05.017
Karpovich N. S., Donchenko L. V., Nelina V. V., Kompantsev V. A., Melnik G. S. Pectin. Production and application. (Kyiv: Urozhai, 1989). [in Russian].
Minzanova S. T., Mironov V. F., Arkhipova D. M., Khabibullina A. V., Mironova L. G., Zakirova Y. M., Milyukov V. A. Biological activity and pharmacological application of pectic polysaccharides: a review. Polymers. 2018. 10(12): 1407. https://doi.org/10.3390/polym10121407
Popova N. V., Lytvynenko V. I., Kutsanyan A. S. Medicinal plants of the world flora. (Kharkiv: Disa plus. 2016). [in Russian].
Lara-Espinoza C., Carvajal-Millán E., Balandrán-Quintana R., López-Franco Y., Rascón-Chu A. Pectin and pectin-based composite materials: beyond food texture. Molecules. 2018. 23(4): 942. https://doi.org/10.3390/molecules23040942
Ovodov Yu. S., Ovodova R. G., Popov S. V., Golovchenko V. V. The latest knowledge on pectin polysaccharides. (Syktyvkar: Publishing House of Komi Scientific Center, Ural Branch of the Russian Academy of Sciences. 2010). [in Russian].
Leclere L., Fransolet M., Cote F., Cambier P., Arnould T., Van Cutsem P., Michiels C. Heat-modied citrus pectin induces apoptosislike cell death and autophagy in HepG2 and A549 cancer cells. PLoS One. 2015. 10(3): e0115831. https://doi.org/10.1371/journal.pone.0115831
Zainal Arin S. H., Yeen W. W., Zainol Abidin I. Z., Abdul Wahab R. M., Arin Z. Z., Sena S. Cytotoxicity effect of degraded and undegraded kappa and iota carrageenan in human intestine and liver cell lines. BMC Complement Altern Med. 2014. 14: e 508. https://doi.org/10.1186/1472-6882-14-508
Razina T. G., Zueva E. P., Amosova E. N., Krylova S. G., Khotimchenko M. Y., Lopatina K. A., Efimova L. A., Safonova E. A., Rybalkina O. Yu. Effects of pectins of various molecular mass on growth of Ehrlich adenocarcinoma and Lewis lung carcinoma, cyclophosphane efficiency in mice. Pacific Medical Journal. 2010. 2(32): 32. [in Russian].
Watanabe K., Reddy B. S., Weisburger J. H., Kritchevsky D. Effect of dietary alfalfa, pectin and wheat bran on azoxymethane- or methylnitrosourea-induced colon carcinogenesis in F344 rats. J. Natl Cancer Inst. 1979. 63(1): 141.
Unger K., Rupprecht H., Valentin B., Kircher W. The use of porous and modified silicas as drug delivery and stabilizing agents. Drug Dev. Ind. Pharm. 1983. 9(1-2): 69. https://doi.org/10.3109/03639048309048546
Daniels R., Kerstiens B., Tischinger-Wagner H., Rupprecht H. The stability of drug adsorbates on silica. Drug Dev. Ind. Pharm. 1986. 12(11-13): 2127 https://doi.org/10.3109/03639048609042627
Slinyakova I. B., Denisova T. I. Organosilicon adsorbents: production, properties, application. (Kyiv: Naukova Dumka. 1988). [in Russian].
The surface properties of silicas. (edited by A.P. Legrand). (New York: Wiley. 1998).
FAO/WHO Codex Alimentarius Commission. List of Additives Evaluated for their Safety-in-Use in Food. CAC/Fal 1-1973.
Gun'ko V. M., Turov V. V., Krupska T. V., Ruban A. N., Kazanets A. I., Leboda R., Skubiszewska-Zieba J. Interfacial behavior of silicone oils interacting with nanosilica and silica gels. J. Colloid and Interface Science. 2013. 394(1): 467. https://doi.org/10.1016/j.jcis.2012.12.026
Krupskaya T. V., Turov V. V., Barvinchenko V. N., Filatova K. O., Suvorova L. A., Iraci G., Kartel M. T. Influence of the "wetting-drying" compaction on the adsorption characteristics of nanosilica A-300. Adsorpt. Sci. Technol. 2017. 36(1-2): 88 https://doi.org/10.1177/0263617417691768
Patent UA 105151. Krupskaya T. V., Turov V. V., Barvinchenko V. M., Filatova K. O., Suvorova L. A., Kartel M. T. The method of compaction of nanosilica. 2016. [in Ukrainian].
State Pharmacopoeia of Ukraine (Kharkiv: RIREG. 2001).
Gerashchenko I.I. Physicochemical aspects of therapeutic effect of enterosorbents (theoretical research). Him. Fiz. Tehnol. Poverhni. 2018. 9(4): 373. https://doi.org/10.15407/hftp09.04.373
Escher W.J., Davis T.A., Klein E. Sorbents and their clinical application. (Kyiv: Nauk. dumka, 1989). [in Russian].
Lukychev B. G., Tsyura V. Y., Panina I. Yu., Avyzova T. S. Enterosorption. (Leningrad: Center of sorption technologies. 1991). [in Russian].
Adsorption from solution at the solid/liquid interface. Edited by G.D. Parfitt, C.H. Rochester. (London; New York: Academic Press. 1983).
Fuzzati N., Gabetta B., Jayakar K., Pace R., Ramaschi G., Villa F. Determination of Ginsenosides in Panax ginseng Roots by Liquid Chromatography with Evaporative Light-Scattering Detection. J AOAC Int. 2000. 83(4): 820. https://doi.org/10.1093/jaoac/83.4.820
Arunotayanun W. Natural product (Fungal and herbal) novel psychoactive substances. In: Dargan P., Wood D., editors. Novel psychoactive substances: Classification, pharmacology and toxicology. (Cambridge, MA: Academic Press. 2013).
Kuypers K. Pc, Ng L., Erritzoe D., Knudsen G. M, Nichols Ch. D, Nichols D. E, Pani L., Soula Anaïs, Nutt D. Microdosing psychedelics: More questions than answers? An overview and suggestions for future research. J Psychopharmacol. 2019. 33(9): 1039. https://doi.org/10.1177/0269881119857204
Toby Lea, Nicole Amada, Henrik Jungaberle, Henrike Schecke, Michael Klein Microdosing psychedelics: Motivations, subjective effects, and harm reduction. Int J Drug Policy. 2020. 75: e102600. https://doi.org/10.1016/j.drugpo.2019.11.008
Grob C. S., Danforth A. L., Chopra G. S., Hagerty M., McKay Ch. R., Halberstadt A. L., Greer G. R. Pilot study of psilocybin treatment for anxiety in patients with advanced-stage cancer. Arch Gen Psychiatry. 2011. 68(1): 71. https://doi.org/10.1001/archgenpsychiatry.2010.116
Davis A. K., Barrett F. S., May D. G., Cosimano M. P., Sepeda N. D., Johnson M. W., Finan P. H., Griffiths R. R. Effects of psilocybin-assisted therapy on major depressive disorder: A randomized clinical trial. JAMA Psychiatry. 2021. 78(5): 481. https://doi.org/10.1001/jamapsychiatry.2020.3285
Petersen J. G., Bergmann R., Krogsgaard-Larsen P., Balle T., Frølund B. Probing the orthosteric binding site of GABAA receptors with heterocyclic GABA carboxylic acid bioisosteres. Neurochemical Research. 2014. 39: 1005. https://doi.org/10.1007/s11064-013-1226-6
Graham A. R. Johnston GABA(A) Receptor Channel Pharmacology. Curr Pharm Des. 2005. 11(15): 1867. https://doi.org/10.2174/1381612054021024
McCarry B. E., Savard Marc A facile synthesis of muscimol. Tetrahedron Lett. 1981. 22(51): 5153. https://doi.org/10.1016/S0040-4039(01)92445-1
Foster A. C. Glutamate- and GABA-based CNS therapeutics. Curr Opin Pharmacol. 2006. 6(1): 7. https://doi.org/10.1016/j.coph.2005.11.005
Dougherty D. A. Cys-loop neuroreceptors: structure to the rescue? Chem Rev. 2008. 108: 1642. https://doi.org/10.1021/cr078207z
Johnston G. A. R., Curtis D. R., de Groat W. C., Duggan A. W. Central actions of ibotenic acid and muscimol. Biochem Pharmacol. 1968. 17(12): 2488. https://doi.org/10.1016/0006-2952(68)90141-X
Krupskaya Т., Paulius J., Bieliauskienė R., Yelahina N., Charmas B., Turov V. Water structure in fungi Amanita musscaria and their composite system 1:9 with hydrocompacted nanosilica A-300. Annales UMCS Sectio AA (Chemia). 2017. 72(2): 26. https://doi.org/10.17951/aa.2017.72.2.25-36
Barthel H., Rösch L., Weis J. Fumed silica - production, properties, and applications. in book Organosilicon Chemistry. 2. From Molecules to Materials / Eds N. Auner J. Weis. (Weinheim: VCH. 1995). https://doi.org/10.1002/9783527619894.ch91
Laskowski J., Kitchener J. A. Hydrophilic-hydrophobic transition on silica. J. Colloid Interface Sci. 1969. 29(4): 670. https://doi.org/10.1016/0021-9797(69)90219-7
Xinhuan Wan, Hao Guo, Yiyu Liang, Changzheng Zhou, Zihao Liu, Kunwei Li, Fengju Niu, Xin Zhai, Lizhu Wang The physiological functions and pharmaceutical applications of inulin: A review. Carbohydrate Polymers. 2020. 246. e116589. https://doi.org/10.1016/j.carbpol.2020.116589
Knyazkova I.I. Potential of inulin in therapeutic practice. Health of Ukraine. 2021. 9: 44. [in Russian]
Barszcz M., Taciak M., Tuśnio A., Święch E., Skomiał J. Dose-dependent effects of two inulin types differing in chain length on the small intestinal morphology, contractility and proinflammatory cytokine gene expression in piglets. Arch Anim Nutr. 2019. 1. https://doi.org/10.1080/1745039X.2019.1697140
Serbaeva E. R., Yakupova A. B., Magasumova Yu. R., Farkhutdinova K. A., Akhmetova G. R., Kuluev B. R. Inulin: natural sources, features of metabolism in plants and practical application. Biomics. 2020. 12(1): 57. https://doi.org/10.31301/2221-6197.bmcs.2020-5
Shoaib M., Shehzad A., Omar M., Rakha A., Raza H., Sharif H. R., Shakeel A., Ansari A., Niazi S. Inulin: properties, health benefits and food applications. Carbohydr Polym. 2016. 147: 444. https://doi.org/10.1016/j.carbpol.2016.04.020
Gao T., Jiao Y., Liu Y., Li T., Wang Z., Wang D. Protective effects of konjac and inulin extracts on type 1 and type 2 diabetes. J Diabetes Res. 2019. e3872182. https://doi.org/10.1155/2019/3872182
Watson A.W., Houghton D., Avery P.J., Stewart C., Vaughan E.E., Meyer P.D., de Bos Kuil M. J. J., Weijs P. J. M., Brandt K. Changes in stool frequency following chicory inulin consumption, and effects on stool consistency, quality of life and composition of gut microbiota. Food Hydrocoll. 2019. 96: 688-698. https://doi.org/10.1016/j.foodhyd.2019.06.006
Guaragni A., Boiago M.M., Bottari N.B., Morsch V.M., Lopes T.F., Schafer da Silva A. Feed supplementation with inulin on broiler performance and meat quality challenged with Clostridium perfringens: Infection and prebiotic impacts. Microb Pathog. 2019. 139. e103889. https://doi.org/10.1016/j.micpath.2019.103889
Nitin Gupta, Ashok Kumar Jangid, Deep Pooja, Hitesh Kulhari Inulin: A novel and stretchy polysaccharide tool for biomedical and nutritional applications. Int. J. of Biol. Macromol. 2019. 132: 852. https://doi.org/10.1016/j.ijbiomac.2019.03.188
Tadesse F. Teferra Possible actions of inulin as prebiotic polysaccharide: A review. Food Frontiers. 2021. 2: 407. https://doi.org/10.1002/fft2.92
Mahmoud M. Tawfick, Hualing Xie, Chao Zhao, Ping Shao, Mohamed A. Farag Inulin fructans in diet: Role in gut homeostasis, immunity, health outcomes and potential therapeutics. Int. J. of Biol. Macromol. 2022. 208. 948. https://doi.org/10.1016/j.ijbiomac.2022.03.218
Mousumi Tudu, Amalesh Samanta Natural polysaccharides: Chemical properties and application in pharmaceutical formulations. Europ. Pol. J. 2023. 184: e111801. https://doi.org/10.1016/j.eurpolymj.2022.111801
Kathy R. Niness Inulin and Oligofructose: What Are They? The J. Nutrition. 1999. 129 (7): 1402S. https://doi.org/10.1093/jn/129.7.1402S
Wasim Akram, Vikas Pandey, Rajeev Sharma, Ramakant Joshi, Neeraj Mishra, Navneet Garud, Tanweer Haider, Inulin: Unveiling its potential as a multifaceted biopolymer in prebiotics, drug delivery, and therapeutics. Internat. J. of Biological Macromol. 2024. 259(1): e129131. https://doi.org/10.1016/j.ijbiomac.2023.129131
Franklin Afinjuomo, Sadikalmahdi Abdella, Souha H Youssef, Yunmei Song, Sanjay Garg Inulin and Its Application in Drug Delivery. Pharmaceuticals (Basel). 2021. 14(9): 855. https://doi.org/10.3390/ph14090855
Tiwari R., Sethi P., Rudrangi S. R. S., Padarthi P. K., Kumar V., Rudrangi S., Vaghela K. J. Inulin: a multifaceted ingredient in pharmaceutical sciences. Biomater Sci Polym Ed. 2024. 29: 1. https://doi.org/10.1080/09205063.2024.2384276
Akram W., Pandey V., Sharma R., Joshi R., Mishra N., Garud N., Haider T., Inulin: Unveiling its potential as a multifaceted biopolymer in prebiotics, drug delivery, and therapeutics. Int J Biol Macromol. 2024. 259(1): e129131. https://doi.org/10.1016/j.ijbiomac.2023.129131
Ghali E. N. H. K., Pranav, Chauhan S. C., Yallapu M. M. Inulin-based formulations as an emerging therapeutic strategy for cancer: A comprehensive review. Int J Biol Macromol. 2024. 259(1) e 129216. https://doi.org/10.1016/j.ijbiomac.2024.129216
Serbaeva E. R., Yakupova A. B., Magasumova Yu. R., Farkhutdinova K. A., Akhmetova G. R., Kuluev B. R. Inulin: natural sources, features of metabolism in plants and practical application. Biomics. 2020. 12(1): 57. https://doi.org/10.31301/2221-6197.bmcs.2020-5
Wancong Li, Jun Zhang, Chunwei Yu, Qing Li, Fang Dong, Gang Wang, Guodong Gu, Zhanyong Guo Extraction, degree of polymerization determination and prebiotic effect evaluation of inulin from Jerusalem artichoke. Carbohydrate Polymers. 2015. 121: 315. https://doi.org/10.1016/j.carbpol.2014.12.055
Fei Luan, Yafei Ji, Lixia Peng, Qi Liu, Haijuan Cao, Yan Yang, Xirui He, Nan Zeng Extraction, purification, structural characteristics and biological properties of the polysaccharides from Codonopsis pilosula: A review. Carbohydrate Polymers. 2021. 261: e117863. https://doi.org/10.1016/j.carbpol.2021.117863
Shaojie Zhang, Ziteng Song, Lijuan Shi, Linan Zhou, Jie Zhang, Jianlin Cui, Yuhao Li, Da-Qing Jin, Yasushi Ohizumi, Jing Xu, Yuanqiang Guo A dandelion polysaccharide and its selenium nanoparticles: Structure features and evaluation of anti-tumor activity in zebrafish models. Carbohydrate Polymers. 2021. 270. e118365. https://doi.org/10.1016/j.carbpol.2021.118365
Kosasih W., Pudjiraharti Sri, Ratnaningrum Diah, Priatni Sri Preparation of Inulin from Dahlia Tubers. Procedia Chemistry. 2015. 16: 190. https://doi.org/10.1016/j.proche.2015.12.035
Escobar F., Sánchez V., Vera E., Ciobotă V., Vargas Jentzsch P., Jaramillo L. Extraction of Inulin from Andean Plants: An Approach to Non-Traditional Crops of Ecuador. Molecules. 2020. 25(21): 5067. https://doi.org/10.3390/molecules25215067
Boeckner L. S., Schnepf M. I., Tungland B. C. Inulin: a review of nutritional and health implications. Advances in Food and Nutrition Research. 2001. 43: 1. https://doi.org/10.1016/S1043-4526(01)43002-6
Le Bastard Q., Chapelet G., Javaudin F., Lepelletier D., Batard E., Montassier E. The effects of inulin on gut microbial composition: a systematic review of evidence from human studies. Eur J Clin Microbiol Infect Dis. 2019. 39: 403. https://doi.org/10.1007/s10096-019-03721-w
Mensink M. A., Frijlink H. W., van der Voort Maarschalk K., Hinrichs W. L. Inulin, a flexible oligosaccharide. II: Review of its pharmaceutical applications. Carbohydr Polym. 2015. 134: 418. https://doi.org/10.1016/j.carbpol.2015.08.022
Mensink M. A., Frijlink H. W., van der Voort Maarschalk K., Hinrichs W. L. J. Inulin, a flexible oligosaccharide I: Review of its physicochemical characteristics. Carbohydrate Polymers. 2015. 130: 405. https://doi.org/10.1016/j.carbpol.2015.05.026
Cooper P. D., Harinda Rajapaksha K., Barclay T. G., Ginic-Markovic M., Gerson A. R., Petrovsky N. Inulin crystal initiation via a glucose-fructose cross-link of adjacent polymer chains: Atomic force microscopy and static molecular modelling. Carbohydrate Polymers. 2015. 117: 964. https://doi.org/10.1016/j.carbpol.2014.10.022
André I., Mazeau K., Tvaroska I., Putaux J.-L., Winter W. T., Taravel F. R., Chanzy H. Molecular and Crystal Structures of Inulin from Electron Diffraction Data. Macromolecules. 1996. 29(13): 4626. https://doi.org/10.1021/ma951799f
Cooper P. D., Barclay T. G., Ginic-Markovic M., Petrovsky N. The polysaccharide inulin is characterized by an extensive series of periodic isoforms with varying biological actions. Glycobiology. 2013. 23(10): 1164. https://doi.org/10.1093/glycob/cwt053
Gun'ko V. M., Lupascu T., Krupska T. V., Golovan A. P., Pakhlov E. M., Turov V. V. Influence of tannin on aqueous layers at a surface of hydrophilic and hydrophobic nanosilicas. Colloids and Surfaces A. 2017. 531(9): 17. https://doi.org/10.1016/j.colsurfa.2017.07.084
Turov V. V., Krupska T. V., Golovan A. P., Andrijko A. P., Tcapko M. D., Ostrovska G. V., Kalmykova G. V., Kartel M. T. Influence of silica on hydratability of the grinded flowers of a hibiscus sabdariffa in neutral and acidic mediums. Nanosystems, Nanomaterials and Nanotechnologies. 2016. 14(4): 643.
Krupska T. V., Turova A. A., Gun'ko V. M., Turov V. V. Influence of highly dispersed materials on physiological activity of yeast cells. Biopolymers and Cell. 2009. 25(4): 290. https://doi.org/10.7124/bc.0007E8
Krupska T. V., Terebinska M. I., Klymenko N. Yu., Vitiuk N. V., Wei Qiliang, Zheng Jinju, Yang Weiyou Turov V. V. Construction of composites for medical purpose based on pyrogenic silica with immobilized succinic acid and their properties. Int J Nanomater Nanotechnol Nanomed. 2024. 10(1): 023. https://doi.org/10.17352/2455-3492.000059
Turov V. V., Gun'ko V. M., Krupska T. V. Hydrophobic agents in nanocomposites for medical purposes. (Kiev: Intersevis. 2023).
Ulrich G. D. Theory of particle formation and growth in oxide synthesis flame. Combust. Sci. Technol. 1971. (4): 47. https://doi.org/10.1080/00102207108952471
Stark W. J. Pratsinis S. E. Aerosol flame reactors for manufacture of nanoparticles. Powder Technol. 2002. 126: 103. https://doi.org/10.1016/S0032-5910(02)00077-3
Tassaing T., Danten Y., Besnard M. Supercritical water: Local or molecular dynamics. Pure Appl. Chem. 2004. 76(1): 133. https://doi.org/10.1351/pac200476010133
Iler R. K. The Chemistry of Silica: Solubility, Polymerization, Colloid and Surface Properties and Biochemistry. (New York: John Wiley and Sons Ltd. 1979).
Turov V. V., Gun'ko V. M., Turova A. A., Morozova L. P., Voronin E. F. Interfacial behavior of concentrated HCl solution and water clustered at a surface of nanosilica in weakly polar solvents media. Colloids Surf. A: Physicochem. Eng. Aspects. 2011. 390(1): 48. https://doi.org/10.1016/j.colsurfa.2011.08.053
Gun'ko V. M., Morozova L. P., Turova A. A., Turov A. V., Gaishun V. E., Bogatyrev V. M., Turov V. V. Hydrated phosphorus oxyacids alone and adsorbed on nanosilica. J. Colloid and Interface Science. 2012. 368: 263. https://doi.org/10.1016/j.jcis.2011.11.018
Product Design and Engineering: Formulation of Gels and Pastes, FirstEdition. Editedby Ulrich Brockel, Willi Meier, and Gerhard Wagner. ©2013 Wiley-VCH Verlag GmbH & Co. KGaA. Published 201 3by Wiley-VCH Verlag GmbH &Co. KGaA.
Koos E., Willenbacher N. Capillary forces in suspension rheology. Science, 2011. 331(6019): 897. https://doi.org/10.1126/science.1199243
Willenbacher N., Vesaratchanon J. S., Thorwarth O., Bartsch E. An alternative route to highly concentrated, freely flowing colloidal dispersions. Soft Matter. 2011. 7: 5777. https://doi.org/10.1039/c1sm05200d
Rebinder P. A. Surface phenomena in dispersed systems: Colloidal chemistry. (M.: Nauka. 1979) [in Russian].
Авторське право (c) 2025 Т. В. Крупська, М. В. Борисенко, Н. Ю. Клименко, Л. В. Зроль, О. А. Новікова, В. В. Туров
Ця робота ліцензується відповідно до Creative Commons Attribution 4.0 International License.
- Автори залишають за собою право на авторство своєї роботи та передають журналу право першої публікації цієї роботи на умовах ліцензії Creative Commons Attribution License, котра дозволяє іншим особам вільно розповсюджувати опубліковану роботу з обов'язковим посиланням на авторів оригінальної роботи та першу публікацію роботи у цьому журналі.
- Автори мають право укладати самостійні додаткові угоди щодо неексклюзивного розповсюдження роботи у тому вигляді, в якому вона була опублікована цим журналом (наприклад, розміщувати роботу в електронному сховищі установи або публікувати у складі монографії), за умови збереження посилання на першу публікацію роботи у цьому журналі.
- Політика журналу дозволяє і заохочує розміщення авторами в мережі Інтернет (наприклад, у сховищах установ або на особистих веб-сайтах) рукопису роботи, як до подання цього рукопису до редакції, так і під час його редакційного опрацювання, оскільки це сприяє виникненню продуктивної наукової дискусії та позитивно позначається на оперативності та динаміці цитування опублікованої роботи.
