Biocompatibility of multi-walled carbon nanotubes and their polymeric nanocomposites
Анотація
There was study the behavior of conglomerates of multy wall carbon nanotubes in water solutions depending on electrolytes or/and biomolecules concentration by the methods of atom force microscopy and electro conductivity. Comparative analysis of atom force microscopy testing the samples polymer’s surfaces: polytetrafluoroethylene, polypropylene and nanocomposites “polytetrafluoroethylene – multy wall carbon nanotubes”, “polypropylene - multy wall carbon nanotubes” in vitro with the reaction of living body on their implantation show that: 1) atom force microscopy may be use as the method of primary compatible testing of new materials; multy wall carbon nanotubes in polymer matrix change nanocomposites surface chemistry and influence on their biocompatibility.
Посилання
Reactions of сonnective tissue to amalgam, intermediate restorative material, mineral trioxide aggregate, and mineral trioxide aggregate mixed with chlorhexidine / M. Sumer, M. Muglali, E. Bodrumlu, Т. Guveng // J. Endodont. – 2006. – V. 32. – P. 1094 – 1096.
Carbon nanotubes as nanomedicines: From toxicology to pharmacology / L. Lacerda, A. Bianco, M. Prato, K. Kostarelos // Adv. Drug Del. Rev. – 2006. – V. 58. –
P. 1460 –1470.
Immunization with peptide-functionalized carbon nanotubes enhances virus-specific neutralizing antibody responses / D. Pantarotto, C.D. Partidos, J. Hoebeke, F. Brown, E. Kramer, J.P. Briand, S. Muller, M. Prato, A. Bianco // Chem. Biol. – 2003. – V. 10. – P. 961 – 966.
Double functionalisation of carbon nanotubes for multimodal drug delivery / G. Pastorin, W. Wu, S. Wieckowski, J.P. Briand, K. Kostarelos, M. Prato, A. Bianco // Chem. Commun. – 2006. – P. 1182 – 1184.
Синтез, структура, физико-химические свойства наноуглеродных материалов / Ю.И. Семенцов, А.В. Мележик, Г.П. Приходько, Н.А. Гаврилюк, М.Л. Пятковський В.В. Янченко // В кн.: Физико-химия наноматериалов и супрамолекулярных структур. Том 2. / Под ред. А.П. Шпака, П.П. Горбика. – Киев: Наук. думка, 2007. – С. 116 – 158.
Stability of the aqueous suspensions of nanotubes in the presence of nonionic surfactant / M. Lisunova, N. Lebovka, O. Melezhyk, Yu. Boiko // J. Coll. Interf. Sci. – 2006. –V. 299. – P. 740 – 746.
Attaching single biomolecules selectively to the apex of AFM tips for measuring specific interactions / J. Gu, Z. Xiao, C-M. Yam, G. Qin, N. Deluge, S. Boutet, C. Cai // J. Biophys. – 2005. –V. 89, № 5. – P. 31 – 33.
